Description

5-Ethynyl-2-Methylpyridine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate. This compound is valued for its versatile reactivity, particularly the ethynyl group, which enables efficient cross-coupling and click chemistry reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and pesticides.
• Material Science Research: Serves as a precursor for functionalized polymers and advanced organic materials.
• Chemical Biology & Bioconjugation: The alkyne functionality makes it suitable for Huisgen cycloaddition (click chemistry) to label biomolecules.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A versatile reagent for synthetic organic chemistry in both discovery and process development laboratories.

Basic Information

Product Name	5-Ethynyl-2-Methylpyridine Hydrochloride
CAS No.	1207351-11-8
Molecular Formula	C8H8ClN
Molecular Weight	153.61 g/mol
Synonyms	2-Methyl-5-ethynylpyridine hydrochloride; 5-Ethynyl-2-picoline hydrochloride; 2-Picoline, 5-ethynyl-, hydrochloride; 2-Methyl-5-ethynylpyridinium chloride
EINECS	Contact for details

Quality Control

Our 5-Ethynyl-2-Methylpyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.