Description

Methyl 2-(Trifluoromethyl)Imidazo-[1,2-A]Pyridine-6-Carboxylate is a high-value heterocyclic building block featuring a fused imidazopyridine core with a trifluoromethyl substituent. This compound is critical for medicinal chemistry research and development, offering a versatile scaffold for creating novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of new drug candidates, particularly in areas like kinase inhibitors and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new active pharmaceutical ingredients (APIs), especially for kinase inhibitors and CNS-targeting drugs.
• Medicinal Chemistry Research: Serves as a privileged scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents, leveraging the biological activity of the imidazopyridine moiety.
• Material Science Research: Investigated as a building block for organic electronic materials and specialty polymers due to its unique electronic properties imparted by the fluorine atoms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	Methyl 2-(Trifluoromethyl)Imidazo-[1,2-A]Pyridine-6-Carboxylate
CAS No.	1206973-10-5
Molecular Formula	C10H7F3N2O2
Molecular Weight	244.17 g/mol
Synonyms	Methyl 2-(trifluoromethyl)imidazo[1,2-a]pyridine-6-carboxylate; 6-(Methoxycarbonyl)-2-(trifluoromethyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-6-carboxylic acid, 2-(trifluoromethyl)-, methyl ester; Methyl 2-trifluoromethylimidazo[1,2-a]pyridine-6-carboxylate; 2-Trifluoromethyl-imidazo[1,2-a]pyridine-6-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(Trifluoromethyl)Imidazo-[1,2-A]Pyridine-6-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is supplied with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.