Description

2-Chloro-5-(Trifluoromethoxy)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced chemical synthesis. Its molecular structure, featuring both chloro and trifluoromethoxy substituents, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group contributes to improved lipophilicity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or novel polymers.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	2-Chloro-5-(Trifluoromethoxy)Pyridine
CAS No.	1206972-45-3
Molecular Formula	C6H3ClF3NO
Molecular Weight	197.54 g/mol
Synonyms	2-Chloro-5-(trifluoromethoxy)pyridine; 5-(Trifluoromethoxy)-2-chloropyridine; 2-Chloro-5-(trifluoromethoxy)pyridine; Pyridine, 2-chloro-5-(trifluoromethoxy)-; 2-Chloro-5-trifluoromethoxypyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-(Trifluoromethoxy)Pyridine is produced and tested under a strict quality management system. We ensure high-purity standards suitable for demanding research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.