Description

6-(2-Aminoethyl)-6,7-Dihydropyrrolo[3,4-B]Pyridin-5-One is a high-purity, advanced pharmaceutical intermediate with a fused pyrrolopyridine core structure. This compound is valued for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Serves as a core structural component in the design and synthesis of potential kinase inhibitors for oncology and inflammatory diseases.
• Bioconjugation & Probe Synthesis: The aminoethyl side chain provides a handle for conjugation, useful in creating fluorescent probes or affinity labels for biochemical assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	6-(2-Aminoethyl)-6,7-Dihydropyrrolo[3,4-B]Pyridin-5-One
CAS No.	1206970-12-8
Molecular Formula	C9H11N3O
Molecular Weight	177.21 g/mol
Synonyms	6-(2-Aminoethyl)-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one; 6-(2-Aminoethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one; 2-(5-Oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-6-yl)ethan-1-amine; 6-(2-Aminoethyl)-5H-pyrrolo[3,4-b]pyridin-5-one, 6,7-dihydro-; Pyrrolo[3,4-b]pyridin-5-one, 6-(2-aminoethyl)-6,7-dihydro-
EINECS	Contact for details

Quality Control

Our 6-(2-Aminoethyl)-6,7-Dihydropyrrolo[3,4-B]Pyridin-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.