Description

(2,8-Diaza-Spiro[4.5]Dec-2-Yl)(2-Fluoro-Phenyl)Methanone is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and diaza structural motif. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting the central nervous system and other therapeutic areas. It is primarily sought after by R&D chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its spirocyclic scaffold.
• Ligand and Probe Development: Serves as a precursor for developing chemical probes to study biological targets and pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations offering custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and new methodology development.

Basic Information

Product Name	(2,8-Diaza-Spiro[4.5]Dec-2-Yl)(2-Fluoro-Phenyl)Methanone
CAS No.	1206969-90-5
Molecular Formula	C₁₅H₁₉FN₂O
Molecular Weight	262.33 g/mol
Synonyms	2-Fluoro-N-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)benzamide; 8-(2-Fluorobenzoyl)-1,4-dioxa-8-azaspiro[4.5]decane; (2-Fluorophenyl)(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methanone; 1,4-Dioxa-8-azaspiro[4.5]decane-8-carboxylic acid (2-fluorophenyl)amide; 1206969-90-5; (2-Fluoro-phenyl)-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-methanone
EINECS	Contact for details

Quality Control

Our (2,8-Diaza-Spiro[4.5]Dec-2-Yl)(2-Fluoro-Phenyl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.