Description

2-Benzyl-1-Oxo-2,5-Diaza-Spiro[3.5]Nonane-5-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and diaza scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of new drug candidates, particularly in areas targeting central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) with potential therapeutic applications.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The diaza-spiro structure is valuable for creating inhibitors targeting specific protease enzymes.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein function.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for bespoke synthetic routes.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and methodology development.

Basic Information

Product Name	2-Benzyl-1-Oxo-2,5-Diaza-Spiro[3.5]Nonane-5-Carboxylic Acid tert-Butyl Ester
CAS No.	1206969-85-8
Molecular Formula	C19H26N2O3
Molecular Weight	330.43 g/mol
Synonyms	tert-Butyl 2-benzyl-1-oxo-2,5-diazaspiro[3.5]nonane-5-carboxylate; 2,5-Diaza-spiro[3.5]nonane-5-carboxylic acid, 2-benzyl-1-oxo-, 1,1-dimethylethyl ester; 2-Benzyl-1-oxo-2,5-diazaspiro[3.5]nonane-5-carboxylic acid tert-butyl ester; 2-Benzyl-2,5-diazaspiro[3.5]nonan-1-one-5-carboxylic acid tert-butyl ester; BOC-protected 2-benzyl-2,5-diazaspiro[3.5]nonan-1-one; 5-(tert-Butoxycarbonyl)-2-benzyl-2,5-diazaspiro[3.5]nonan-1-one
EINECS	Contact for details

Quality Control

Our production of 2-Benzyl-1-Oxo-2,5-Diaza-Spiro[3.5]Nonane-5-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity assessment by HPLC. Certificates of Analysis (COA) detailing all critical quality attributes are provided with each shipment. Our quality system is designed to support cGMP-compliant applications for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.