Description

5-(4-(1,3-Dioxan-2-Yl)-3-Fluorophenyl)-2-Chloropyridine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Agrochemical Research: Potential intermediate in the development of new generation pesticides and herbicides requiring fluorinated aromatic systems.
• Material Science: Exploration of applications in organic electronic materials due to its conjugated pyridine and fluorinated phenyl structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	5-(4-(1,3-Dioxan-2-Yl)-3-Fluorophenyl)-2-Chloropyridine
CAS No.	1206969-79-0
Molecular Formula	C15H13ClFNO2
Molecular Weight	293.72 g/mol
Synonyms	2-Chloro-5-[4-(1,3-dioxan-2-yl)-3-fluorophenyl]pyridine; 5-(4-(1,3-Dioxan-2-yl)-3-fluorophenyl)-2-chloropyridine; 2-Chloro-5-(3-fluoro-4-(1,3-dioxan-2-yl)phenyl)pyridine; 1206969-79-0; 5-(4-(1,3-Dioxolan-2-yl)-3-fluorophenyl)-2-chloropyridine (common name variant); 2-Chloropyridine, 5-[4-(1,3-dioxan-2-yl)-3-fluorophenyl]-; CAS 1206969-79-0
EINECS	Contact for details

Quality Control

Our 5-(4-(1,3-Dioxan-2-Yl)-3-Fluorophenyl)-2-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.