Description

2,6-Diazaspiro[3.5]Nonane-6-Carboxylic Acid, 1-Oxo-2-(Phenylmethyl)-, 1,1-Dimethylethyl Ester is a sophisticated spirocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of potential drug candidates, particularly in protease inhibitor and central nervous system (CNS) targeted therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Peptidomimetic Synthesis: Serves as a constrained scaffold to mimic peptide secondary structures, enhancing metabolic stability and bioavailability.
• Agrochemical Development: Employed in the research phase for creating novel herbicides or fungicides with specific modes of action.
• Chemical Biology Probes: Utilized to develop tool compounds for studying enzyme function and biological pathways.
• Asymmetric Synthesis: Acts as a source of chirality and structural complexity in catalytic asymmetric transformations.

Basic Information

Product Name	2,6-Diazaspiro[3.5]Nonane-6-Carboxylic Acid, 1-Oxo-2-(Phenylmethyl)-, 1,1-Dimethylethyl Ester
CAS No.	1206969-63-2
Molecular Formula	C19H26N2O3
Molecular Weight	330.43 g/mol
Synonyms	tert-Butyl 1-oxo-2-benzyl-2,6-diazaspiro[3.5]nonane-6-carboxylate; 2,6-Diazaspiro[3.5]nonane-6-carboxylic acid, 1-oxo-2-(phenylmethyl)-, 1,1-dimethylethyl ester; 2-Benzyl-1-oxo-2,6-diazaspiro[3.5]nonane-6-carboxylic acid tert-butyl ester; 1-Oxo-2-benzyl-2,6-diazaspiro[3.5]nonane-6-carboxylic acid tert-butyl ester; tert-Butyl 2-benzyl-1-oxo-2,6-diazaspiro[3.5]nonane-6-carboxylate; Spirocyclic Diazanone Ester; Chiral Spirocyclic Building Block
EINECS	Contact for details

Quality Control

Our high-value chemical building blocks are produced under strict quality management systems to ensure batch-to-batch consistency and purity for research applications. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as chiral purity, chemical purity, and identity confirmation. We adhere to cGMP principles where applicable for advanced intermediates destined for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.