Description

8-(Chloromethyl)-3-(Tetrahydrofuran-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine is a high-value, heterocyclic organic compound featuring a fused triazolopyridine core with chloromethyl and tetrahydrofuran substituents. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug discovery pipelines.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for constructing complex drug molecules, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with potential therapeutic benefits.
• Preclinical Drug Development: Employed in the synthesis of candidate compounds for pharmacological and toxicological evaluation.
• Agrochemical Intermediate: Potential use in the research and development of novel pesticides and herbicides due to its heterocyclic structure.
• Material Science Research: Can be investigated as a monomer or precursor for specialty polymers and functional materials.

Basic Information

Product Name	8-(Chloromethyl)-3-(Tetrahydrofuran-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	1206969-57-4
Molecular Formula	C12H14ClN3O
Molecular Weight	251.71 g/mol
Synonyms	8-(Chloromethyl)-3-(tetrahydro-2-furanyl)-[1,2,4]triazolo[4,3-a]pyridine; 3-(Oxolan-2-yl)-8-(chloromethyl)-[1,2,4]triazolo[4,3-a]pyridine; 1206969-57-4; [1,2,4]Triazolo[4,3-a]pyridine, 8-(chloromethyl)-3-(tetrahydro-2-furanyl)-; 8-(Chloromethyl)-3-(tetrahydrofuran-2-yl)-[1,2,4]triazolo[4,3-a]pyridine
EINECS	Contact for details

Quality Control

Our production of 8-(Chloromethyl)-3-(Tetrahydrofuran-2-Yl)-[1,2,4]Triazolo[4,3-A]Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.