Description

6-Chloro-5-Cyanonicotinic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific heterocyclic scaffolds.
• Material Science Research: Serves as a precursor for functionalized organic materials and ligands for metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up process development.

Basic Information

Product Name	6-Chloro-5-Cyanonicotinic Acid
CAS No.	1206969-20-1
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	6-Chloro-5-cyanopyridine-3-carboxylic acid; 3-Carboxy-6-chloro-5-cyanopyridine; 5-Cyano-6-chloronicotinic acid; 6-Chloro-5-cyano-3-pyridinecarboxylic acid; Nicotinic acid, 6-chloro-5-cyano-; 1206969-20-1; 6-Chloro-5-cyanopyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Cyanonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.