Description

Methyl 2,4-Difluoro-3-Methylbenzoate is a high-purity fluorinated aromatic ester building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those containing difluoromethyl and benzoate motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic chemicals for display and lighting technologies.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions, esterifications, and as a substrate for developing new fluorination methodologies in academic and industrial research.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymer backbones, enhancing material properties like chemical resistance and thermal stability.

Basic Information

Product Name	Methyl 2,4-Difluoro-3-Methylbenzoate
CAS No.	1206675-31-1
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	2,4-Difluoro-3-methylbenzoic acid methyl ester; Methyl 2,4-difluoro-3-methylbenzoate; Benzoic acid, 2,4-difluoro-3-methyl-, methyl ester; 3-Methyl-2,4-difluorobenzoic acid methyl ester; Methyl 3-methyl-2,4-difluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2,4-Difluoro-3-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.