Description

Methyl 2-(4-Chlorophenyl)-2-Fluoroacetate is a high-purity fluorinated organic ester building block, essential for advanced synthetic chemistry. Its core value lies in providing a versatile and reactive scaffold for introducing both fluorinated and chlorinated aromatic motifs into target molecules. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in CNS and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides with enhanced activity and environmental profiles.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialty polymers with unique surface properties.
• Ligand and Catalyst Development: Employed in the preparation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the biological effects of fluorine incorporation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	Methyl 2-(4-Chlorophenyl)-2-Fluoroacetate
CAS No.	1206631-87-9
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	Methyl (4-chlorophenyl)(fluoro)acetate; 2-Fluoro-2-(4-chlorophenyl)acetic acid methyl ester; Methyl α-fluoro-4-chlorophenylacetate; 4-Chloro-α-fluorobenzeneacetic acid methyl ester; Methyl 2-fluoro-2-(4-chlorophenyl)acetate; (4-Chlorophenyl)(fluoro)acetic acid methyl ester; Methyl 4-chloro-α-fluorophenylacetate
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-Chlorophenyl)-2-Fluoroacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications from research to commercial-scale cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.