Description

Thiazolo[4,5-B]Pyridine, 2-Bromo- is a high-value brominated heterocyclic building block, essential for advanced organic synthesis and pharmaceutical research. Its core value lies in enabling the construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromo-functionalization for further cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the thiazolopyridine scaffold imparts specific biological activity.
• Material Science: Acts as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological systems.
• Cross-Coupling Reactions: The bromo-substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Ligand Synthesis: Useful for preparing novel nitrogen-sulfur containing ligands for catalysis.

Basic Information

Product Name	Thiazolo[4,5-B]Pyridine, 2-Bromo-
CAS No.	1206249-91-3
Molecular Formula	C6H3BrN2S
Molecular Weight	215.07 g/mol
Synonyms	2-Bromothiazolo[4,5-b]pyridine; 2-Bromo[1,3]thiazolo[4,5-b]pyridine; 2-Bromo-thiazolo[4,5-b]pyridine; Thiazolo[4,5-b]pyridine, 2-bromo-; 1206249-91-3; AKOS026710893; 2-bromo-thiazolo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our Thiazolo[4,5-B]Pyridine, 2-Bromo- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.