Description

tert-Butyl (6-Bromo-4-Methylpyridin-2-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated pyridine core and carbamate protecting group. This compound matters as a critical building block in modern organic synthesis, enabling the efficient construction of complex molecules for drug discovery and development. It is primarily needed by research institutions and pharmaceutical companies engaged in the creation of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and oncological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Synthesis Building Block: The bromine atom provides a versatile handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group is utilized for the temporary protection of amines during complex synthetic sequences.
• Agrochemical Research: Potential application in the development of novel pesticides and herbicides due to its heterocyclic structure.
• Material Science Precursor: Can be employed in the synthesis of specialized ligands for catalysts or functional organic materials.

Basic Information

Product Name	tert-Butyl (6-Bromo-4-Methylpyridin-2-Yl)Carbamate
CAS No.	1206249-13-9
Molecular Formula	C11H15BrN2O2
Molecular Weight	287.15 g/mol
Synonyms	Boc-6-Bromo-4-methyl-2-aminopyridine; 2-((tert-Butoxycarbonyl)amino)-6-bromo-4-methylpyridine; tert-Butyl N-(6-bromo-4-methyl-2-pyridinyl)carbamate; 6-Bromo-4-methylpyridin-2-amine, N-Boc protected; (6-Bromo-4-methylpyridin-2-yl)carbamic acid tert-butyl ester; 2-Amino-6-bromo-4-methylpyridine N-Boc derivative; BOC-6-Br-4-Me-Py-2-NH2
EINECS	Contact for details

Quality Control

Our tert-Butyl (6-Bromo-4-Methylpyridin-2-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.