Description

2-Bromo-5-Chlorothiazolo[4,5-B]Pyridine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its unique thiazolopyridine scaffold.
• Material Science: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed as a molecular probe or a tag in bioconjugation chemistry due to its reactive halogen sites.
• Custom Synthesis: A critical building block for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	2-Bromo-5-Chlorothiazolo[4,5-B]Pyridine
CAS No.	1206248-02-3
Molecular Formula	C6H2BrClN2S
Molecular Weight	249.52 g/mol
Synonyms	2-Bromo-5-chloro[1,3]thiazolo[4,5-b]pyridine; Thiazolo[4,5-b]pyridine, 2-bromo-5-chloro-; 1206248-02-3; 2-Bromo-5-chlorothiazolo[4,5-b]pyridine; 5-Chloro-2-bromothiazolo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chlorothiazolo[4,5-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.