Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Chloro-4-Hydroxy- is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a functionalized, fused-ring scaffold essential for constructing complex molecules with targeted biological activity. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, particularly in medicinal chemistry programs focused on kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially for kinase-targeted therapies.
• Medicinal Chemistry: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Serves as a precursor in the creation of new herbicides, fungicides, or insecticides with specific modes of action.
• Chemical Research: Employed in academic and industrial labs for exploring new heterocyclic chemistry and reaction methodologies.
• Bioconjugation & Probe Development: The carboxylic acid group allows for coupling to other molecules, useful in creating biochemical probes or labeled compounds.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Chloro-4-Hydroxy-
CAS No.	1204476-05-0
Molecular Formula	C8H5ClN2O3
Molecular Weight	212.59 g/mol
Synonyms	3-Chloro-4-hydroxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 3-Chloro-4-hydroxypyrrolo[2,3-b]pyridine-2-carboxylic acid; 3-Chloro-4-hydroxy-1H-7-azaindole-2-carboxylic acid; 3-Chloro-4-hydroxy-7-azaindole-2-carboxylic acid; 3-Chloro-4-hydroxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 1204476-05-0; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-chloro-4-hydroxy-
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Chloro-4-Hydroxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive and should be stored away from light. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.