Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 4-Methoxy-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound serves as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Oncology Drug Discovery: Used in the synthesis of kinase inhibitors and other targeted cancer therapies due to its privileged heterocyclic scaffold.
• CNS-Active Compound Synthesis: Employed in creating molecules for neurological and psychiatric disorder research.
• Agrochemical Research: Serves as a building block for developing novel crop protection agents and pesticides.
• Material Science: Potential use in the synthesis of organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 4-Methoxy-, Methyl Ester
CAS No.	1204476-03-8
Molecular Formula	C10H10N2O3
Molecular Weight	206.20 g/mol
Synonyms	4-Methoxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; Methyl 4-methoxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 4-Methoxy-1H-7-azaindole-2-carboxylic acid methyl ester; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 4-methoxy-, methyl ester; 1204476-03-8; 4-Methoxy-7-azaindole-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 4-Methoxy-, Methyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects with material suitable for use under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.