Description

1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-chloro- is a high-value, halogenated heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its fused pyrrolopyridine core enables the creation of complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: A critical scaffold for synthesizing kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its bioactive heterocyclic structure.
• Material Science Precursor: Serves as a building block for organic electronic materials and functional polymers.
• Chemical Biology Probes: Employed in the design of molecular probes and ligands for studying biological systems and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and library production.

Basic Information

Product Name	1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-chloro-
CAS No.	1204475-64-8
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	3-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 3-Chloro-2-carboxy-7-azaindole; 3-Chloro-7-azaindole-2-carboxylic acid; 3-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 3-Chloro-2-carboxy-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-1H-7-azaindole-2-carboxylic acid; 3-Chloro-2-carboxy-1H-7-azaindole
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-chloro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.