Description

Methyl 2-Bromo-5-Fluoro-4-Methylbenzoate CAS NO 1204304-98-2 is a high-purity, multi-functional halogenated benzoate ester, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile aromatic scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for molecules targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or modifier in the production of specialty polymers and high-performance engineering plastics.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new chemical spaces in medicinal and synthetic chemistry.
• Custom Synthesis & Contract Manufacturing: A vital intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific molecules on scale.

Basic Information

Product Name	Methyl 2-Bromo-5-Fluoro-4-Methylbenzoate
CAS No.	1204304-98-2
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	2-Bromo-5-fluoro-4-methylbenzoic acid methyl ester; Methyl 2-bromo-5-fluoro-p-toluate; Benzoic acid, 2-bromo-5-fluoro-4-methyl-, methyl ester; 4-Methyl-2-bromo-5-fluorobenzoic acid methyl ester; Methyl 4-methyl-2-bromo-5-fluorobenzoate; 2-Bromo-5-fluoro-4-methyl methylbenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-5-Fluoro-4-Methylbenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent lot-to-lot quality. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.