Description

2-Bromo-5-Trifluoromethylsulfanyl-Pyridine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining bromine and a trifluoromethylthio group on the pyridine ring, makes it an essential intermediate for introducing specific functionalities into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethylthio group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl systems.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Life Science Research: Employed as a biochemical tool and probe in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Bromo-5-Trifluoromethylsulfanyl-Pyridine
CAS No.	1204234-94-5
Molecular Formula	C6H3BrF3NS
Molecular Weight	258.06 g/mol
Synonyms	2-Bromo-5-(trifluoromethylthio)pyridine; 5-(Trifluoromethylthio)-2-bromopyridine; Pyridine, 2-bromo-5-[(trifluoromethyl)thio]-; 2-Bromo-5-(trifluoromethylsulfanyl)pyridine; 2-Bromopyridin-5-yl trifluoromethyl sulfide; 2-Bromo-5-(trifluoromethylsulfanyl)pyridine; 2-Bromo-5-(trifluoromethylthio)pyridine; 1204234-94-5
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Trifluoromethylsulfanyl-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents	Complies with ICH guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.