Description

2-(2-Azidoethoxy)Ethanamine Hcl is a specialized organic compound featuring both an azide functional group and a primary amine hydrochloride salt. This unique bifunctional structure makes it a valuable building block for click chemistry and bioconjugation applications, enabling the formation of stable triazole linkages under mild conditions. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotech, and materials science sectors for developing targeted drug delivery systems, diagnostic probes, and advanced polymeric materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Bioconjugation Reagent: Used for site-specific labeling of proteins, peptides, and oligonucleotides with fluorescent dyes, affinity tags, or other payloads.
• Polymer Chemistry: Serves as a functional monomer or cross-linker for creating smart hydrogels, surface coatings, and functionalized nanomaterials with tailored properties.
• Chemical Biology Probes: Enables the development of activity-based probes for studying enzyme function and metabolic pathways in live cells.
• Diagnostic Agent Synthesis: Employed in the construction of contrast agents and molecular imaging probes for PET, MRI, and fluorescence imaging.
• Material Surface Modification: Facilitates the covalent attachment of bioactive molecules to surfaces for biosensor and tissue engineering applications.

Basic Information

Product Name	2-(2-Azidoethoxy)Ethanamine Hcl
CAS No.	1204085-45-9
Molecular Formula	C4H11N4O•HCl
Molecular Weight	182.62 g/mol
Synonyms	2-(2-Azidoethoxy)ethan-1-amine hydrochloride; N-(2-Azidoethoxyethyl)amine hydrochloride; Azido-PEG2-amine hydrochloride; 2,2'-(Azidoimino)bis[ethanol] hydrochloride; Amino-PEG2-azide HCl; 1-Azido-2-[2-aminoethoxy]ethane hydrochloride; PEG2 azide amine HCl; AEAA HCl
EINECS	Contact for details

Quality Control

Our 2-(2-Azidoethoxy)Ethanamine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. Due to its hygroscopic and light-sensitive nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.