Description

2,6-Diazaspiro[4.5]decan-1-one hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic amine class. This compound is a critical building block in modern medicinal chemistry, valued for its unique three-dimensional structure that can enhance the binding affinity and metabolic stability of drug candidates. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing complex molecules in drug discovery programs.
• CNS Drug Development: Employed in the synthesis of potential therapeutics targeting neurological disorders.
• Oncology Research: Serves as a building block for novel small-molecule cancer therapies.
• Chemical Biology: Utilized as a probe or ligand in studying biological pathways and protein interactions.
• Process Chemistry: Scaled up for use in route development and optimization for commercial API manufacturing.

Basic Information

Product Name	2,6-Diazaspiro[4.5]decan-1-one hydrochloride
CAS No.	1203686-81-0
Molecular Formula	C8H15N2O·HCl
Molecular Weight	190.68 g/mol
Synonyms	1-Oxo-2,6-diazaspiro[4.5]decane hydrochloride; 2,6-Diazaspiro[4.5]decan-1-one HCl; 1-Oxo-2,6-diazaspiro[4.5]decane HCl; Spiro[4.5]decan-1-one, 2,6-diaza-, hydrochloride; 2,6-Diazaspiro[4.5]decan-1-one monohydrochloride; 2,6-Diazaspiro[4.5]decan-1-one hydrochloride salt
EINECS	Contact for details

Quality Control

Our 2,6-Diazaspiro[4.5]decan-1-one hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.