Description

6'-Fluoro-2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Isoquinoline] is a high-value, fluorinated spirocyclic compound featuring a unique molecular architecture that combines an isoquinoline moiety with a cyclopropane ring. This structure is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key synthetic intermediate or a pharmacologically active scaffold. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic effects.
• Agrochemical Development: Acts as a precursor in the research and synthesis of new-generation pesticides and herbicides with improved efficacy.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to create complex, fluorinated organic molecules for various high-value applications.
• Academic & Institutional Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6'-Fluoro-2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Isoquinoline]
CAS No.	1203685-57-7
Molecular Formula	C12H12FN
Molecular Weight	189.23 g/mol
Synonyms	6'-Fluoro-1'H-spiro[cyclopropane-1,4'-isoquinoline]; 6'-Fluoro-2',3'-dihydrospiro[cyclopropane-1,4'-isoquinoline]; 6-Fluoro-2,3-dihydro-1H-spiro[cyclopropane-1,4'-isoquinoline]; Spiro[cyclopropane-1,4'-isoquinoline], 6'-fluoro-2',3'-dihydro-1'H-; 1203685-57-7; 6'-Fluoro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4-isoquinoline]; 6'-Fluoro-1'H-spiro[cyclopropane-1,4'-isoquinoline] (2',3'-dihydro)
EINECS	Contact for details

Quality Control

Our 6'-Fluoro-2',3'-Dihydro-1'H-Spiro[Cyclopropane-1,4'-Isoquinoline] is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. We provide comprehensive analytical data including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) are available for every batch upon request, detailing purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.