Description

1,7-Diazaspiro[4.5]Decan-6-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel APIs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Used as a specialized building block for constructing complex heterocyclic and spirocyclic molecular architectures.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the development and scale-up of custom synthesis projects.
• Academic Research: Employed in university and institutional labs for studying synthetic methodologies and new chemical reactions.

Basic Information

Product Name	1,7-Diazaspiro[4.5]Decan-6-One Hydrochloride
CAS No.	1203682-21-6
Molecular Formula	C8H15ClN2O
Molecular Weight	190.67 g/mol
Synonyms	1,7-Diazaspiro[4.5]decan-6-one, hydrochloride; 6-Oxo-1,7-diazaspiro[4.5]decane hydrochloride; 1,7-Diazaspiro[4.5]decan-6-one HCl; Spiro[4.5]decan-6-one, 1,7-diaza-, hydrochloride; 1203682-21-6; 1,7-Diazaspiro[4.5]decan-6-one monohydrochloride
EINECS	Contact for details

Quality Control

Our 1,7-Diazaspiro[4.5]Decan-6-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.