Description

2,7-Diazaspiro[4.4]Nonan-1-One Hydrochloride is a high-purity, heterocyclic organic compound with a unique spirocyclic structure, serving as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key scaffold and building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its constrained, three-dimensional geometry.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds and probes to study biological pathways and protein function.
• Agrochemical Synthesis: Employed as an intermediate in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Development for Catalysis: Utilized in the design and synthesis of novel chiral ligands for asymmetric catalysis.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers with specific thermal or mechanical properties.

Basic Information

Product Name	2,7-Diazaspiro[4.4]Nonan-1-One Hydrochloride
CAS No.	1203682-17-0
Molecular Formula	C7H13N2O·HCl
Molecular Weight	176.65 g/mol
Synonyms	1-Oxo-2,7-diazaspiro[4.4]nonane hydrochloride; 2,7-Diazaspiro[4.4]nonan-1-one, hydrochloride; 2,7-Diazaspiro[4.4]nonane-1-one HCl; Spiro[4.4]nonane-1-one, 2,7-diaza-, hydrochloride; 1203682-17-0; 2,7-Diazaspiro[4.4]nonan-1-one monohydrochloride
EINECS	Contact for details

Quality Control

Our 2,7-Diazaspiro[4.4]Nonan-1-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.