Description

2-Pyrimidinamine, 4-(4-Chloro-6-Methoxy-3H-Pyrrolo[2,3-B]Pyridin-3-Yl)- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for novel therapeutic agents. It is primarily utilized by pharmaceutical companies and research institutions focused on developing small molecule drugs targeting various disease pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for clinical research.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Building block for potential inhibitors targeting specific kinase enzymes involved in cellular signaling.
• Oncology Therapeutics: Research component for developing targeted cancer therapies due to its privileged pyrrolopyridine-pyrimidine structure.
• Chemical Biology Probes: Used in the development of molecular probes to study biological processes and disease mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	2-Pyrimidinamine, 4-(4-Chloro-6-Methoxy-3H-Pyrrolo[2,3-B]Pyridin-3-Yl)-
CAS No.	1203569-96-3
Molecular Formula	C12H10ClN5O
Molecular Weight	275.70 g/mol
Synonyms	4-(4-Chloro-6-methoxy-3H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine; 4-(4-Chloro-6-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-pyrimidinamine; 1203569-96-3; 4-(4-Chloro-6-methoxypyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine; 4-(4-Chloro-6-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine; 3-(2-Aminopyrimidin-4-yl)-4-chloro-6-methoxy-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.