Description

(E)-Methyl 3-(2-Fluoro-6-(Pyrrolidin-1-Yl)Pyridin-3-Yl)Acrylate is a high-purity, fluorinated pyridine derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and versatile building block for the development of novel active ingredients. It is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and material science sectors seeking to incorporate complex heterocyclic structures into their products.

Application

This specialized acrylate ester is a key precursor in the synthesis of complex molecules. Its primary and potential applications include:

• Pharmaceutical Intermediate: A crucial building block in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides that require fluorinated heterocyclic components for enhanced activity and stability.
• Chemical Research: Serves as a versatile reagent in organic synthesis for constructing complex molecular architectures in academic and industrial R&D settings.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and functional materials that incorporate photoactive or electron-deficient moieties.
• Ligand and Catalyst Development: The pyrrolidinyl-pyridine core can be utilized to develop novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	(E)-Methyl 3-(2-Fluoro-6-(Pyrrolidin-1-Yl)Pyridin-3-Yl)Acrylate
CAS No.	1203500-11-1
Molecular Formula	C13H15FN2O2
Molecular Weight	250.27 g/mol
Synonyms	Methyl (2E)-3-[2-Fluoro-6-(1-pyrrolidinyl)-3-pyridinyl]-2-propenoate; (E)-Methyl 3-(2-fluoro-6-(pyrrolidin-1-yl)pyridin-3-yl)acrylate; 2-Propenoic acid, 3-[2-fluoro-6-(1-pyrrolidinyl)-3-pyridinyl]-, methyl ester, (2E)-; Methyl (E)-3-(2-fluoro-6-(pyrrolidin-1-yl)pyridin-3-yl)acrylate; 1203500-11-1; Methyl 3-(2-fluoro-6-(pyrrolidin-1-yl)pyridin-3-yl)acrylate (E)-isomer
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-(2-Fluoro-6-(Pyrrolidin-1-Yl)Pyridin-3-Yl)Acrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.