Description

6-(3-Hydroxyprop-1-Ynyl)-1H-Pyrido-[2,3-B][1,4]Oxazin-2(3H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly within oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• API Synthesis: Serves as a core scaffold for constructing final active pharmaceutical ingredients, especially those targeting specific enzymatic pathways.
• Biochemical Research: Employed as a tool compound or probe in biochemical assays to study biological mechanisms and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical development from preclinical to commercial stages.
• Academic Research: Utilized in university and institutional labs for the development of new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	6-(3-Hydroxyprop-1-Ynyl)-1H-Pyrido-[2,3-B][1,4]Oxazin-2(3H)-One
CAS No.	1203499-41-5
Molecular Formula	C10H8N2O3
Molecular Weight	204.18 g/mol
Synonyms	6-(3-Hydroxy-1-propyn-1-yl)-3,4-dihydro-1H-pyrido[2,3-b][1,4]oxazin-2-one; 6-(3-Hydroxyprop-1-yn-1-yl)-1H,2H,3H,4H-pyrido[2,3-b][1,4]oxazine-2-one; 6-(3-Hydroxyprop-1-ynyl)-3,4-dihydro-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one; 1203499-41-5; Pyrido[2,3-b][1,4]oxazin-2(3H)-one, 6-(3-hydroxy-1-propyn-1-yl)-3,4-dihydro-
EINECS	Contact for details

Quality Control

Our production of 6-(3-Hydroxyprop-1-Ynyl)-1H-Pyrido-[2,3-B][1,4]Oxazin-2(3H)-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with the specifications agreed upon with our clients. Our quality systems are designed to support cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C limits
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.