Description

tert-Butyl 3-Allyl-4-Chloropyridin-2-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine core functionalized with allyl, chloro, and carbamate protecting groups. This compound matters as a critical building block in modern organic synthesis, enabling the efficient construction of complex molecules for drug discovery and development. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile reactive sites.
• API Development: Serves as a crucial precursor in the development of Active Pharmaceutical Ingredients, especially for kinase inhibitors and other targeted therapies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target engagement.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and herbicides.

Basic Information

Product Name	tert-Butyl 3-Allyl-4-Chloropyridin-2-Ylcarbamate
CAS No.	1203499-30-2
Molecular Formula	C13H17ClN2O2
Molecular Weight	268.74 g/mol
Synonyms	tert-Butyl N-(3-allyl-4-chloropyridin-2-yl)carbamate; 2-Pyridinecarboxamide, N-(3-allyl-4-chloro-2-pyridinyl)-, 1,1-dimethylethyl ester; Carbamic acid, N-(3-allyl-4-chloro-2-pyridinyl)-, 1,1-dimethylethyl ester; 3-Allyl-4-chloro-N-(tert-butoxycarbonyl)pyridin-2-amine; BOC-3-Allyl-4-chloro-2-aminopyridine; tert-Butyl (3-allyl-4-chloropyridin-2-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Allyl-4-Chloropyridin-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.