Description

Methyl 1-(4-Methoxybenzyl)-2-Oxo-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1203499-28-8. This compound is a critical building block in modern medicinal chemistry, valued for its complex heterocyclic structure which serves as a key scaffold in drug discovery and development. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.

Application

This specialized intermediate is designed for high-value synthetic applications within the pharmaceutical and fine chemical industries.

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Integral in the process development and scale-up of new active pharmaceutical ingredients (APIs) requiring the pyridooxazine moiety.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical market.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Methyl 1-(4-Methoxybenzyl)-2-Oxo-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazine-6-Carboxylate
CAS No.	1203499-28-8
Molecular Formula	C17H16N2O5
Molecular Weight	328.32 g/mol
Synonyms	Methyl 1-[(4-methoxyphenyl)methyl]-2-oxo-3H-pyrido[2,3-b][1,4]oxazine-6-carboxylate; 1-(4-Methoxybenzyl)-2-oxo-1,2-dihydro-3H-pyrido[2,3-b][1,4]oxazine-6-carboxylic acid methyl ester; 6-Carbomethoxy-1-(4-methoxybenzyl)-1,2-dihydro-3H-pyrido[2,3-b][1,4]oxazin-2-one; CAS 1203499-28-8; Pyrido[2,3-b][1,4]oxazine-6-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our production of Methyl 1-(4-Methoxybenzyl)-2-Oxo-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazine-6-Carboxylate adheres to stringent quality protocols suitable for pharmaceutical R&D. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.