Description

Methyl 1-Benzyl-4-(3-Methyl-3H-Imidazo-[4,5-B]Pyridin-6-Yl)Pyrrolidine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily required by research institutions and pharmaceutical companies engaged in the development of small molecule drugs targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent, selective kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns for drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for creating labeled analogs used in pharmacological assays.
• Contract Development and Manufacturing (CDMO): Supplied to CDMOs for scale-up synthesis under current Good Manufacturing Practice (cGMP) conditions for clinical trial material production.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Methyl 1-Benzyl-4-(3-Methyl-3H-Imidazo-[4,5-B]Pyridin-6-Yl)Pyrrolidine-3-Carboxylate
CAS No.	1203499-27-7
Molecular Formula	C21H22N4O2
Molecular Weight	362.43 g/mol
Synonyms	1-Benzyl-4-(3-methyl-3H-imidazo[4,5-b]pyridin-6-yl)pyrrolidine-3-carboxylic acid methyl ester; Methyl 1-benzyl-4-(3-methylimidazo[4,5-b]pyridin-6-yl)pyrrolidine-3-carboxylate; 6-[1-Benzyl-3-(methoxycarbonyl)pyrrolidin-4-yl]-3-methyl-3H-imidazo[4,5-b]pyridine; CAS 1203499-27-7
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets the exacting standards required for pharmaceutical R&D. Our quality commitment aligns with ISO 9001 principles, and custom synthesis can be performed under controlled conditions suitable for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.