Description

1-(5-Bromo-3-Nitropyridin-2-Yl)Piperazine is a high-purity, advanced pharmaceutical intermediate characterized by its bromo-nitropyridine core linked to a piperazine moiety. This compound is of significant value for its role as a versatile building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new drug candidates, especially within therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products.
• Chemical Biology: Serves as a valuable probe or linker in the study of protein-ligand interactions and biochemical pathways.
• Material Science: Potential building block for the creation of specialized polymers or organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1-(5-Bromo-3-Nitropyridin-2-Yl)Piperazine
CAS No.	1203499-08-4
Molecular Formula	C9H11BrN4O2
Molecular Weight	287.12 g/mol
Synonyms	1-(5-Bromo-3-nitropyridin-2-yl)piperazine; 2-Piperazino-5-bromo-3-nitropyridine; 5-Bromo-3-nitro-2-piperazin-1-ylpyridine; Piperazine, 1-(5-bromo-3-nitro-2-pyridinyl)-; 1203499-08-4
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-3-Nitropyridin-2-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.