Description

5-Chloro-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate in modern organic chemistry. Its core value lies in its fused pyrrolopyridine scaffold, which is a privileged structure for designing bioactive molecules with targeted pharmacological properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase-targeted oncology and anti-inflammatory drugs.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, amide bond formation, and other transformations to create complex molecular architectures.
• Material Science Research: Investigated as a potential precursor for organic electronic materials and ligands in catalytic systems.

Basic Information

Product Name	5-Chloro-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid
CAS No.	1203498-99-0
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 5-Chloro-3-carboxy-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 3-Carboxy-5-chloro-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-7-azaindole-3-carboxylic acid; 5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate; 1203498-99-0; 5-Cl-1H-Pyrrolo[2,3-b]pyridine-3-COOH
EINECS	Contact for details

Quality Control

Our 5-Chloro-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.