Description

(E)-1-(4-Chlorophenyl)-3-(4-Hydroxy-3-Methoxyphenyl)-2-Propen-1-One Hydrate is a high-purity, synthetic chalcone derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a versatile and critical building block for developing novel bioactive molecules, particularly due to its distinct structural motifs. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the discovery of new therapeutic agents, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting inflammation, cancer, and metabolic disorders.
• Biochemical Research: Used as a reference standard or probe in enzymatic inhibition studies and structure-activity relationship (SAR) investigations.
• Agrochemical Development: Serves as a core structure for synthesizing new-generation pesticides and plant growth regulators.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique optical or electronic properties.
• Academic Research: Employed in organic chemistry laboratories for studying chalcone chemistry, condensation reactions, and heterocyclic synthesis.

Basic Information

Product Name	(E)-1-(4-Chlorophenyl)-3-(4-Hydroxy-3-Methoxyphenyl)-2-Propen-1-One Hydrate
CAS No.	1202866-96-3
Molecular Formula	C16H13ClO3 • xH2O
Molecular Weight	288.72 (Anhydrous basis)
Synonyms	(E)-1-(4-Chlorophenyl)-3-(4-Hydroxy-3-methoxyphenyl)prop-2-en-1-one Hydrate; 2-Propen-1-one, 1-(4-chlorophenyl)-3-(4-hydroxy-3-methoxyphenyl)-, (E)-, Hydrate; 4'-Chloro-3-hydroxy-4-methoxychalcone Hydrate; p-Chlorophenyl 4-Hydroxy-3-methoxystyryl Ketone Hydrate; NSC 760446 (Hydrate); Chalcone Derivative Hydrate
EINECS	Contact for details

Quality Control

Our (E)-1-(4-Chlorophenyl)-3-(4-Hydroxy-3-Methoxyphenyl)-2-Propen-1-One Hydrate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF for water content, to ensure it meets the stringent requirements of research and development. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.