Description

tert-Butyl 1H,4H,5H,6H,7H-Imidazo[4,5-C]Pyridine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its imidazo[4,5-c]pyridine core structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Oncology Drug Development: Used in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Employed in creating novel compounds aimed at neurological and psychiatric disorders.
• Chemical Biology Probes: Acts as a core structure for developing tool compounds to study biological pathways and protein function.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke molecules for clients.

Basic Information

Product Name	tert-Butyl 1H,4H,5H,6H,7H-Imidazo[4,5-C]Pyridine-5-Carboxylate
CAS No.	1202800-68-7
Molecular Formula	C11H15N3O2
Molecular Weight	221.26 g/mol
Synonyms	5-tert-Butoxycarbonyl-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridine; tert-Butyl 1,4,5,6,7-pentahydroimidazo[4,5-c]pyridine-5-carboxylate; 1H,4H,5H,6H,7H-Imidazo[4,5-c]pyridine-5-carboxylic acid, 1,1-dimethylethyl ester; Boc-protected imidazopyridine; Imidazo[4,5-c]pyridine-5-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 1H,4H,5H,6H,7H-Imidazo[4,5-C]Pyridine-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP guidelines suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.