Description

6-Bromo-2',3',5',6'-Tetrahydrospiro[Indoline-3,4'-Pyran] is a high-value, advanced pharmaceutical intermediate characterized by its unique spirocyclic molecular architecture. This compound is of significant interest for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the research and synthesis of new-generation pesticides and herbicides with spirocyclic motifs.
• Organic Synthesis Building Block: Provides a functionalized spiro[indoline-3,4'-pyran] core for constructing complex natural product analogs and functional materials.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	6-Bromo-2',3',5',6'-Tetrahydrospiro[Indoline-3,4'-Pyran]
CAS No.	1202765-56-7
Molecular Formula	C13H14BrNO
Molecular Weight	280.16 g/mol
Synonyms	6-Bromo-2,3,5,6-tetrahydrospiro[indoline-3,4'-pyran]; 6-Bromospiro[indoline-3,4'-pyran]; 6-Bromo-1,2,3,5,6,7-hexahydrospiro[indole-3,4'-pyran]; 6-Bromo-2,3,5,6-tetrahydro-1H-spiro[indole-3,4'-pyran]; 6-Bromo-2,3,5,6-tetrahydrospiro[1H-indole-3,4'-pyran]; 6-Bromo-2,3,5,6-tetrahydrospiro[indoline-3,4'-pyran] (CAS 1202765-56-7)
EINECS	Contact for details

Quality Control

Our 6-Bromo-2',3',5',6'-Tetrahydrospiro[Indoline-3,4'-Pyran] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.