Description

5,6,7,8-Tetrahydro-2,6-Naphthyridin-1(2H)-One Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant interest in modern organic synthesis. This compound matters for its critical role in the research and development of novel active pharmaceutical ingredients (APIs), particularly within the central nervous system and oncology therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for constructing complex molecular architectures, enabling the discovery of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly for neurological and oncological targets.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing novel naphthyridine-based heterocyclic compounds.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Bioconjugation & Probe Development: Potential use in creating biochemical probes for studying biological pathways and target engagement.

Basic Information

Product Name	5,6,7,8-Tetrahydro-2,6-Naphthyridin-1(2H)-One Hydrochloride
CAS No.	1201785-01-4
Molecular Formula	C8H11ClN2O
Molecular Weight	186.64 g/mol
Synonyms	1,2,3,4-Tetrahydro-2,6-naphthyridin-1-one hydrochloride; 5,6,7,8-Tetrahydro-2,6-naphthyridin-1-ol hydrochloride; 2,6-Naphthyridin-1(2H)-one, 5,6,7,8-tetrahydro-, hydrochloride; Tetrahydro-2,6-naphthyridinone HCl; CAS 1201785-01-4
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-2,6-Naphthyridin-1(2H)-One Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support our clients' regulatory needs with traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.