Description

n-Benzyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinamide is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex heterocyclic and biphenyl motifs.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in academic and industrial R&D laboratories.
• Ligand & Catalyst Synthesis: Used to construct sophisticated ligand frameworks for catalysis and metal-organic complexes.

Basic Information

Product Name	n-Benzyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinamide
CAS No.	1201644-43-0
Molecular Formula	C20H25BN2O3
Molecular Weight	352.24 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-benzylpicolinamide; N-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxamide; 2-Pyridinecarboxamide, N-benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(phenylmethyl)-2-pyridinecarboxamide; Pinacol N-Benzyl-5-boronopicolinamide ester
EINECS	Contact for details

Quality Control

Our n-Benzyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.