Description

2-(5-Methylpyridin-2-Yl)Acetic Acid Hydrochloride is a high-purity organic salt, primarily utilized as a critical pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its value lies in its role as a versatile building block for constructing complex molecules, particularly in medicinal chemistry and drug discovery programs. This compound is essential for research institutions, CROs/CDMOs, and pharmaceutical manufacturers focused on developing new therapeutic agents, especially within the fields of neurology and inflammation.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug discovery.
• Chemical Synthesis: Serves as a precursor for the preparation of more complex heterocyclic compounds and functionalized pyridine derivatives.
• Contract Research & Manufacturing: Supplied to CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) for client projects.
• Reference Standard: Can be used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2-(5-Methylpyridin-2-Yl)Acetic Acid Hydrochloride
CAS No.	1201194-56-0
Molecular Formula	C8H9NO2 • HCl
Molecular Weight	187.62 g/mol (Free base: 151.16 g/mol)
Synonyms	2-(5-Methyl-2-pyridinyl)acetic acid hydrochloride; (5-Methylpyridin-2-yl)acetic acid HCl; 2-(5-Methyl-2-pyridyl)acetic acid hydrochloride; 5-Methyl-2-pyridineacetic acid hydrochloride; 2-Pyridineacetic acid, 5-methyl-, hydrochloride; 1201194-56-0; 2-(5-Methylpyridin-2-yl)ethanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-(5-Methylpyridin-2-Yl)Acetic Acid Hydrochloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical R&D and synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and other relevant analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.