Description

6-Chloro-4-(Trifluoromethyl)Nicotinonitrile is a high-value, multi-functional heterocyclic building block, identified by CAS NO 1201187-18-9. This compound is critical for its role in facilitating complex molecular transformations in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethylpyridine core.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing molecular probes, enzyme inhibitors, and labeled compounds for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-Chloro-4-(Trifluoromethyl)Nicotinonitrile
CAS No.	1201187-18-9
Molecular Formula	C7H2ClF3N2
Molecular Weight	206.55 g/mol
Synonyms	6-Chloro-4-(trifluoromethyl)pyridine-3-carbonitrile; 3-Cyano-6-chloro-4-(trifluoromethyl)pyridine; 6-Chloro-4-trifluoromethylnicotinonitrile; 6-Chloro-4-trifluoromethyl-3-pyridinecarbonitrile; 6-Chloro-4-(trifluoromethyl)-3-pyridinecarbonitrile; 6-Chloro-4-(trifluoromethyl)nicotinonitrile; 1201187-18-9
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-(Trifluoromethyl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.