Description

(1S,2R,4S,5R,6S)-3,8-Dioxatricyclo[3.2.1.02,4]Octane-6-Carboxylic Acid Methyl Ester is a high-purity, chiral bicyclic lactone derivative with a complex, rigid molecular framework. This compound is a valuable synthetic intermediate and building block in advanced organic chemistry, prized for its stereochemical precision and functional group versatility. It is primarily sought after by research institutions and pharmaceutical companies for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in stereoselective reactions to construct molecules with defined three-dimensional configurations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the discovery of new therapeutic agents.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of fine chemicals.
• Academic Research: Applied in methodological studies and the synthesis of novel molecular architectures in university and institutional labs.
• Ligand and Catalyst Precursor: Potential use in the development of chiral ligands or organocatalysts for catalytic asymmetric transformations.

Basic Information

Product Name	(1S,2R,4S,5R,6S)-3,8-Dioxatricyclo[3.2.1.02,4]Octane-6-Carboxylic Acid Methyl Ester
CAS No.	1199940-75-4
Molecular Formula	C9H12O4
Molecular Weight	184.19 g/mol
Synonyms	Methyl (1S,2R,4S,5R,6S)-3,8-dioxatricyclo[3.2.1.02,4]octane-6-carboxylate; (1S,2R,4S,5R,6S)-rel-3,8-Dioxatricyclo[3.2.1.02,4]octane-6-carboxylic acid methyl ester; Bicyclic lactone methyl ester; 3,8-Dioxatricyclo[3.2.1.02,4]octane-6-carboxylic acid, methyl ester, (1S,2R,4S,5R,6S)-
EINECS	Contact for details

Quality Control

Our (1S,2R,4S,5R,6S)-3,8-Dioxatricyclo[3.2.1.02,4]Octane-6-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry, to ensure high chemical and enantiomeric purity and identity. Certificates of Analysis (COA) with detailed specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.