Description

L-Tyrosine, O,3-Dimethyl-n-[(Phenylmethoxy)Carbonyl]-, Methyl Ester is a sophisticated, high-purity chemical intermediate derived from the amino acid L-Tyrosine. This compound is critical for research and development in advanced pharmaceutical synthesis, particularly in the construction of complex peptide-based molecules and active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel peptide drugs, enzyme inhibitors, and other bioactive compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new therapeutic candidates targeting various diseases.
• Process Chemistry: Serves as a protected and functionalized starting material for scalable API synthesis under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation: Potential use in creating antibody-drug conjugates (ADCs) or other targeted drug delivery systems due to its reactive ester group.
• Academic & Institutional R&D: Employed in universities and research institutes for fundamental studies in organic synthesis and biochemistry.

Basic Information

Product Name	L-Tyrosine, O,3-Dimethyl-n-[(Phenylmethoxy)Carbonyl]-, Methyl Ester
CAS No.	1199794-65-4
Molecular Formula	C20H23NO5
Molecular Weight	357.40 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-O,3-dimethyl-L-tyrosine methyl ester; Z-O,3-dimethyl-L-Tyr-OMe; Methyl N-[(benzyloxy)carbonyl]-O,3-dimethyl-L-tyrosinate; (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-(4-hydroxy-2,6-dimethylphenyl)propanoic acid methyl ester; Cbz-O,3-dimethyl-L-tyrosine methyl ester; N-Carbobenzoxy-O,3-dimethyl-L-tyrosine methyl ester; Protected L-Tyrosine derivative; Z-Dmt(Me2)-OMe
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for research and pharmaceutical applications. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and high chemical purity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment. We support development projects requiring material produced under GMP-like guidelines for non-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.