Description

4,7-Diazaspiro[2.5]Octan-5-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting central nervous system and other therapeutic areas. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in hit-to-lead optimization and the construction of spirocyclic compound libraries for biological screening.
• Proteolysis Targeting Chimera (PROTAC) Development: Potential linker or component in the design of bifunctional degraders.
• Chemical Biology Probes: Serves as a scaffold for developing tools to study enzyme function and biological pathways.
• Agrochemical Research: Intermediate in the development of new crop protection agents with novel modes of action.
• Academic Research: Used in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4,7-Diazaspiro[2.5]Octan-5-One Hydrochloride
CAS No.	1199794-52-9
Molecular Formula	C6H11N3O·HCl
Molecular Weight	177.63 g/mol
Synonyms	5-Oxo-4,7-diazaspiro[2.5]octane hydrochloride; 4,7-Diazaspiro[2.5]octan-5-one, hydrochloride; 4,7-Diazaspiro[2.5]octane-5-one HCl; 5-Oxo-4,7-diazaspiro[2.5]octane HCl; Spiro[cyclopropane-1,4'-piperidine]-2',5'-dione hydrochloride (unsubstituted); 1-Azaspiro[2.5]octane-2,5-dione hydrochloride derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4,7-Diazaspiro[2.5]Octan-5-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.