Description

(R)-5-Methyl-4,7-Diazaspiro[2.5]Octane 2Hcl is a high-purity, chiral spirocyclic diamine building block of significant interest in modern pharmaceutical research and development. Its unique three-dimensional, rigid structure makes it a valuable scaffold for designing novel active pharmaceutical ingredients (APIs) with enhanced selectivity and metabolic stability. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study enzyme function and protein-protein interactions.
• Agrochemical Research: Employed in the discovery of new, more selective pesticides and herbicides due to its spirocyclic architecture.
• Peptidomimetics: Incorporated into peptide analogs to confer conformational restraint and improve pharmacological properties.
• Academic & Contract Research: Essential for exploratory synthetic chemistry and methodology development in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	(R)-5-Methyl-4,7-Diazaspiro[2.5]Octane 2Hcl
CAS No.	1199792-83-0
Molecular Formula	C7H16N2 • 2HCl
Molecular Weight	213.13 g/mol
Synonyms	(5R)-5-Methyl-4,7-diazaspiro[2.5]octane dihydrochloride; (R)-5-Methyl-4,7-diazaspiro[2.5]octane hydrochloride (1:2); (R)-5-Methyl-4,7-diazaspiro[2.5]octane 2HCl; (R)-5-Methyl-4,7-diazaspiro[2.5]octane dihydrochloride; 4,7-Diazaspiro[2.5]octane, 5-methyl-, (5R)-, dihydrochloride; UNII-9F4Q8T3Q1K; (R)-5-Methyl-4,7-diazaspiro[2.5]octane bis(hydrochloride)
EINECS	Contact for details

Quality Control

Our (R)-5-Methyl-4,7-Diazaspiro[2.5]Octane 2Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical data including HPLC purity, chiral purity (enantiomeric excess), and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications and test results are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.