Description

1-(3,5-Dimethoxyphenyl)-2,2,2-Trifluoroethylamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoroethylamine and dimethoxyphenyl structure. This compound is critical for the synthesis of complex molecules, offering a versatile building block for introducing specific functional groups and fluorine atoms into target structures. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine moiety enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships (SAR) in medicinal chemistry due to its trifluoroethyl group.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and electronic chemicals.
• Academic & R&D: Utilized in university and corporate laboratories for methodological development and exploratory synthesis.

Basic Information

Item	Detail
Product Name	1-(3,5-Dimethoxyphenyl)-2,2,2-Trifluoroethylamine
CAS No.	1199782-97-2
Molecular Formula	C10H12F3NO2
Molecular Weight	235.20 g/mol
Synonyms	1-(3,5-Dimethoxyphenyl)-2,2,2-trifluoroethanamine; 2,2,2-Trifluoro-1-(3,5-dimethoxyphenyl)ethanamine; 3,5-Dimethoxy-α-(trifluoromethyl)benzylamine; α-(Trifluoromethyl)-3,5-dimethoxybenzylamine; 2,2,2-Trifluoro-1-(3,5-dimethoxyphenyl)ethylamine; (3,5-Dimethoxyphenyl)(trifluoromethyl)methylamine; TFMPA-DM Derivative
EINECS	Contact for details

Quality Control

Our 1-(3,5-Dimethoxyphenyl)-2,2,2-Trifluoroethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent composition. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.