Description

n-((1-(2-(tert-Butylamino)-2-Oxoethyl)Piperidin-4-Yl)Methyl)-3-Chloro-5-Fluorobenzamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated molecular scaffold for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic molecules.
• API Synthesis: Serves as a precursor in the multi-step synthesis of complex active pharmaceutical ingredients requiring a piperidine-benzamide core structure.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	n-((1-(2-(tert-Butylamino)-2-Oxoethyl)Piperidin-4-Yl)Methyl)-3-Chloro-5-Fluorobenzamide
CAS No.	1199236-64-0
Molecular Formula	C19H27ClFN3O2
Molecular Weight	383.89 g/mol
Synonyms	3-Chloro-5-fluoro-N-[[1-[2-[(1,1-dimethylethyl)amino]-2-oxoethyl]-4-piperidinyl]methyl]benzamide; 3-Chloro-5-fluoro-N-((1-(2-(tert-butylamino)-2-oxoethyl)piperidin-4-yl)methyl)benzamide; Benzamide, 3-chloro-5-fluoro-N-[[1-[2-[(1,1-dimethylethyl)amino]-2-oxoethyl]-4-piperidinyl]methyl]-; CAS 1199236-64-0; N-((1-(2-(tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide
EINECS	Contact for details

Quality Control

Our n-((1-(2-(tert-Butylamino)-2-Oxoethyl)Piperidin-4-Yl)Methyl)-3-Chloro-5-Fluorobenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.