Description

2-Chloro-6-Cyclopropylnicotinonitrile is a high-value, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a chloro and a nitrile group on the pyridine core, makes it an essential intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine scaffold.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Serves as a starting material for creating molecular probes to study biological pathways and protein functions.
• Custom Synthesis Building Block: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring functionalized heterocycles.

Basic Information

Product Name	2-Chloro-6-Cyclopropylnicotinonitrile
CAS No.	1198475-35-2
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	2-Chloro-6-cyclopropylpyridine-3-carbonitrile; 6-Cyclopropyl-2-chloronicotinonitrile; 3-Cyano-2-chloro-6-cyclopropylpyridine; 2-Chloro-6-cyclopropyl-3-cyanopyridine; Nicotinonitrile, 2-chloro-6-cyclopropyl-; 1198475-35-2
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Cyclopropylnicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.