Description

6-Azaspiro[3.5]Nonane Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical manufacturing seeking to develop new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel chemical libraries in high-throughput screening and lead optimization.
• Process Chemistry Development: Serves as a starting material for scaling up the production of candidate drugs under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in the custom synthesis of complex organic molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for studying spirocyclic compound reactivity and developing new synthetic methodologies.

Basic Information

Product Name	6-Azaspiro[3.5]Nonane Hydrochloride
CAS No.	1198285-07-2
Molecular Formula	C8H16ClN
Molecular Weight	161.67 g/mol
Synonyms	6-Azaspiro[3.5]nonane, hydrochloride; 6-Azaspiro[3.5]nonane HCl; 1-Azaspiro[4.4]nonane hydrochloride; Azaspiro[3.5]nonane hydrochloride; Spiro[cyclopentane-1,3'-pyrrolidine] hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Azaspiro[3.5]Nonane Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and commercial projects with material suitable for research use and can provide material manufactured under ICH Q7-aligned GMP standards for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.