Description

2-Boc-2,9-Diazaspiro[5.5]undecan-1-one is a high-purity, protected diazaspirocyclic building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of complex molecules, particularly for drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries seeking to build novel molecular scaffolds with precise stereochemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, especially for neurological targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to explore novel chemical space.
• Process Research & Development: Serves as a starting material or advanced intermediate in the scale-up and route scouting for Active Pharmaceutical Ingredients (APIs).
• Proteolysis Targeting Chimera (PROTAC) Development: Utilized as a component in the linker or ligand design for targeted protein degradation platforms.
• Chemical Biology Probes: Incorporated into tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects.

Basic Information

Product Name	2-Boc-2,9-Diazaspiro[5.5]undecan-1-one
CAS No.	1198284-94-4
Molecular Formula	C14H24N2O3
Molecular Weight	268.35 g/mol
Synonyms	1-tert-Butyl 2-oxo-2,9-diazaspiro[5.5]undecane-1,9-dicarboxylate; 2,9-Diazaspiro[5.5]undecan-1-one, 2-[(1,1-dimethylethoxy)carbonyl]-; 2-(tert-Butoxycarbonyl)-2,9-diazaspiro[5.5]undecan-1-one; Boc-Protected Diazaspiro Undecanone; 2-Boc-2,9-diazaspiro[5.5]undecane-1-one; tert-Butyl 1-oxo-2,9-diazaspiro[5.5]undecane-2-carboxylate; 2,9-Diazaspiro[5.5]undecane-1-one, N-Boc-protected
EINECS	Contact for details

Quality Control

Our 2-Boc-2,9-Diazaspiro[5.5]undecan-1-one is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and can provide material to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.