Description

3-Boc-7-Oxo-3-Azaspiro[5.5]Undecane is a high-purity, protected spirocyclic amine building block of significant interest in advanced organic synthesis. Its core value lies in its rigid, three-dimensional scaffold and the presence of orthogonal protecting groups, making it a critical intermediate for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and protease inhibitor research.
• Agrochemical Research: Used in the development of new herbicides and pesticides with novel modes of action due to its complex spirocyclic structure.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study enzyme function and protein-protein interactions.
• Peptidomimetics: The 3-azaspiro[5.5]undecane core is a valuable non-peptide scaffold for mimicking peptide secondary structures.
• Material Science: Potential precursor for specialty polymers and ligands used in catalysis and separation sciences.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring high-fidelity chiral intermediates.

Basic Information

Product Name	3-Boc-7-Oxo-3-Azaspiro[5.5]Undecane
CAS No.	1198284-49-9
Molecular Formula	C15H25NO3
Molecular Weight	267.36 g/mol
Synonyms	tert-Butyl 7-oxo-3-azaspiro[5.5]undecane-3-carboxylate; 3-(tert-Butoxycarbonyl)-3-azaspiro[5.5]undecan-7-one; 3-Boc-3-azaspiro[5.5]undecan-7-one; 3-Azaspiro[5.5]undecan-7-one, 3-[(1,1-dimethylethoxy)carbonyl]-; 3-N-Boc-7-oxo-3-azaspiro[5.5]undecane; Boc-3-aza-7-oxo-spiro[5.5]undecane; 7-Oxo-3-azaspiro[5.5]undecane-3-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-Boc-7-Oxo-3-Azaspiro[5.5]Undecane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with research and cGMP-grade material requirements for preclinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.